Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring.

Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring.

Early life events can significantly alter the development of the nociceptive circuit. In fact, clinical work has shown that maternal adversity, in the form of depression, and concomitant selective serotonin reuptake inhibitor (SSRI) treatment influence nociception in infants. The combined effects of...

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Bibliographic Details
Main Authors: Liesbeth Knaepen, Ine Rayen, Thierry D Charlier, Marianne Fillet, Virginie Houbart, Maarten van Kleef, Harry W Steinbusch, Jacob Patijn, Dick Tibboel, Elbert A Joosten, Jodi L Pawluski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23437400/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23437400/pdf/?tool=EBI

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