The use of chitosan-coated flexible liposomes as a remarkable carrier to enhance the antitumor efficacy of 5-fluorouracil against colorectal cancer

Surface-coated nanocarriers have been extensively used to enhance the delivery of anticancer drugs and improve their therapeutic index. In this study, chitosan (CS)-coated flexible liposomes (chitosomes) containing 5-fluorouracil (5-FU) were designed and characterized for use as a novel approach to...

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Bibliographic Details
Main Authors: Abdullah Alomrani, Mohamed Badran, Gamaleldin I. Harisa, Mohamed ALshehry, Moayed Alhariri, Aws Alshamsan, Musaed Alkholief
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419300374