Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities. Here, we show that different phenothiazine derivatives and pyronine G inhibited the activ...

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Bibliographic Details
Main Authors: Shiying Wu, Guanzhong Mao, Leif A. Kirsebom
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/6/3/38