Gut Microbiota Regulates Mincle Mediated Activation of Lung Dendritic Cells to Protect Against Mycobacterium tuberculosis

Gut Microbiota Regulates Mincle Mediated Activation of Lung Dendritic Cells to Protect Against Mycobacterium tuberculosis

Gut microbial components serve as ligand for various pattern recognition receptors (PRRs) present on immune cells and thereby regulates host immunity. Dendritic cells (DCs) are highly specialized innate cells involved in immune response to Mycobacterium tuberculosis (Mtb) infection. The gut-lung axi...

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Bibliographic Details
Main Authors: Shikha Negi, Susanta Pahari, Hilal Bashir, Javed N. Agrewala
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
gut-lung axis
antibiotics
mincle
tuberculosis
lung dendritic cells
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01142/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01142/full

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