Bifurcation kinetics of drug uptake by Gram-negative bacteria.

Bifurcation kinetics of drug uptake by Gram-negative bacteria.

Cell envelopes of many bacteria consist of two membranes studded with efflux transporters. Such organization protects bacteria from the environment and gives rise to multidrug resistance. We report a kinetic model that accurately describes the permeation properties of this system. The model predicts...

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Bibliographic Details
Main Authors: David A Westfall, Ganesh Krishnamoorthy, David Wolloscheck, Rupa Sarkar, Helen I Zgurskaya, Valentin V Rybenkov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5604995?pdf=render

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http://europepmc.org/articles/PMC5604995?pdf=render

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