Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells

Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells

Abstract Background Activation of c-Met, a receptor tyrosine kinase, induces radiation therapy resistance in non-small cell lung cancer (NSCLC). The activated residual of c-Met is located in lipid rafts (Duhon et al. Mol Carcinog 49:739-49, 2010). Therefore, we hypothesized that disturbing the integ...

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Bibliographic Details
Main Authors: Juan Zeng, Heying Zhang, Yonggang Tan, Cheng Sun, Yusi Liang, Jinyang Yu, Huawei Zou
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Lipid rafts
Mesenchymal-epithelial transition factor (c-met)
C-Src
Radiation resistance
NSCLC
Online Access:http://link.springer.com/article/10.1186/s12885-018-4501-8

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http://link.springer.com/article/10.1186/s12885-018-4501-8

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