False positives in trans-eQTL and co-expression analyses arising from RNA-sequencing alignment errors [version 2; peer review: 3 approved]

Sequence similarity among distinct genomic regions can lead to errors in alignment of short reads from next-generation sequencing. While this is well known, the downstream consequences of misalignment have not been fully characterized.  We assessed the potential for incorrect alignment of RNA-sequen...

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Bibliographic Details
Main Authors: Ashis Saha, Alexis Battle
Format: Article
Language:English
Published: F1000 Research Ltd 2019-04-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1860/v2