Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease.

Alzheimer's disease (AD) is an ageing-related neurodegenerative disease characterized and diagnosed by deposition of insoluble amyloid-β (Aβ) plaques in the brain. The plaque accumulation in the brain directly affects reduced levels of Aβ in cerebrospinal fluid (CSF) and blood, as Aβ can freely...

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Bibliographic Details
Main Authors: Da Eun Kwak, Taeho Ko, Han Seok Koh, Yong Woo Ji, Jisu Shin, Kyeonghwan Kim, Hye Yun Kim, Hyung-Keun Lee, YoungSoo Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227618