A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years.

A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years.

Current influenza vaccines have reduced immunogenicity and are of uncertain efficacy in older adults. We assessed the safety and immunogenicity of MVA-NP+M1, a viral-vectored influenza vaccine designed to boost memory T cell responses, in a group of older adults.Thirty volunteers (aged 50-85) receiv...

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Bibliographic Details
Main Authors: Richard D Antrobus, Patrick J Lillie, Tamara K Berthoud, Alexandra J Spencer, James E McLaren, Kristin Ladell, Teresa Lambe, Anita Milicic, David A Price, Adrian V S Hill, Sarah C Gilbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485192?pdf=render

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http://europepmc.org/articles/PMC3485192?pdf=render

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