Structure of the human lipid-gated cation channel TRPC3

The TRPC channels are crucially involved in store-operated calcium entry and calcium homeostasis, and they are implicated in human diseases such as neurodegenerative disease, cardiac hypertrophy, and spinocerebellar ataxia. We present a structure of the full-length human TRPC3, a lipid-gated TRPC me...

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Bibliographic Details
Main Authors: Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/36852