New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin.

Previous studies have shown that the JAK2/STAT3 signaling pathway plays a regulatory role in cellular oxidative stress injury (OSI). In this study, we explored the role of the JAK2/STAT3 signaling pathway in hydrogen peroxide (H2O2)-induced OSI and the protective effect of melatonin against (H2O2)-i...

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Bibliographic Details
Main Authors: Weixun Duan, Yang Yang, Wei Yi, Juanjuan Yan, Zhenxin Liang, Ning Wang, Yue Li, Wensheng Chen, Shiqiang Yu, Zhenxiao Jin, Dinghua Yi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590213?pdf=render