Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1

Abstract Angulin proteins are a group of evolutionally conserved type I transmembrane proteins that contain an extracellular Ig-like domain. In mammals, three angulin proteins have been identified, namely immunoglobulin-like domain containing receptor 1 (ILDR1), immunoglobulin-like domain containing...

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Bibliographic Details
Main Authors: Yueyue Liu, Hongyun Nie, Chengcheng Liu, Xiaoyan Zhai, Qing Sang, Yanfei Wang, Deli Shi, Lei Wang, Zhigang Xu
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07530-z