Overcoming the Limits of Flash Nanoprecipitation: Effective Loading of Hydrophilic Drug into Polymeric Nanoparticles with Controlled Structure

Overcoming the Limits of Flash Nanoprecipitation: Effective Loading of Hydrophilic Drug into Polymeric Nanoparticles with Controlled Structure

Flash nanoprecipitation (FNP) is a widely used technique to prepare particulate carriers based on various polymers, and it was proven to be a promising technology for the industrial production of drug loaded nanoparticles. However, up to now, only its application to hydrophobic compounds has been de...

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Bibliographic Details
Main Authors: Daniele Massella, Edvige Celasco, Fabien Salaün, Ada Ferri, Antonello A. Barresi
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Polymers
Subjects:
nanoparticles
caffeine
flash nanoprecipitation
solvent displacement
drug delivery
PCL
CIJM
encapsulation efficiency
hydrophilic compound
surface properties
Online Access:http://www.mdpi.com/2073-4360/10/10/1092

Internet

http://www.mdpi.com/2073-4360/10/10/1092

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