Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma

Background and aim. Trophoblast cell surface antigen 2 (TROP2) or tumor-associated calcium signal transducer 2 (TACSTD2) is a 36-kDa type I transmembrane glycoprotein and exerts dual functions as an oncogene and tumor suppressor in cancer cells. In this study, we investigated the expression and func...

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Bibliographic Details
Main Authors: Kanlayanee Sawanyawisuth, Ph.D., Nattawat Tantapotinan, Ratthaphol Kraiklang, Anucha Puapairoj, Chaisiri Wongkham, Gregory J. Riggins, Sopit Wongkham
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119307434