SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways

SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways

Abstract Background The SUMO-activating enzyme SAE1 is indispensable for protein SUMOylation. A dysregulation of SAE1 expression involves in progression of several human cancers. However, its biological roles of SAE1 in glioma are unclear by now. Methods The differential proteome between human gliom...

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Bibliographic Details
Main Authors: Yanfang Yang, Ziwei Liang, Zijing Xia, Xixi Wang, Yanni Ma, Zenghua Sheng, Qingjia Gu, Guobo Shen, Liangxue Zhou, Hongxia Zhu, Ningzhi Xu, Shufang Liang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cell Communication and Signaling
Subjects:
Glioma
SAE1
SUMOylation
Phosphorylation
Akt signaling pathway
Online Access:http://link.springer.com/article/10.1186/s12964-019-0392-9

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http://link.springer.com/article/10.1186/s12964-019-0392-9

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