Beta-adrenergic agonist protects retinal pigment epithelium against hydroxycholoroquine toxicity via cAMP-PKA signal pathway

AIM: To test our hypothesis that activation of protein kinase A (PKA) signal pathway by β-adrenergic agonist plays an important role in the protecting of cultured retinal pigment epithelial (RPE) cells against the hydroxychloroquine (HCQ) toxicity. METHODS: Cultured human RPE cells were treated wit...

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Bibliographic Details
Main Authors: Ruihua Zhang, Dan-Ning Hu, Richard Rosen
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-04-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2020/4/20200404.pdf