Effects of epithelial to mesenchymal transition on T cell targeting of melanoma cells.

Effects of epithelial to mesenchymal transition on T cell targeting of melanoma cells.

Melanoma cells can switch phenotype in a manner similar to epithelial to mesenchymal transition(EMT). In this perspective article, we address the effects of such phenotype switching on T cell targeting of tumour cells. During the EMT-like switch in phenotype, a concomitant change in expression of mu...

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Bibliographic Details
Main Authors: Katherine eWoods, Anupama ePasam, Aparna eJayachandran, Miles eAndrews, Jonathan eCebon
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Oncology
Subjects:
Melanoma
T-Lymphocytes
Tumor antigens
Epithelial-mesenchymal transition (EMT)
T-cell killing
Cancer testis antigens
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00367/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00367/full

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