The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis.

Multidrug- and extensively drug-resistant tuberculosis have emerged as grave threats to public health worldwide. Very few active drugs are available or likely to become available soon. To address these problems we revisited a classical observation, the applicability of phenothiazines as antimicrobia...

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Bibliographic Details
Main Authors: Dick van Soolingen, Rogelio Hernandez-Pando, Hector Orozco, Diana Aguilar, Cecile Magis-Escurra, Leonard Amaral, Jakko van Ingen, Martin J Boeree
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20844587/?tool=EBI