Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

Polymer-based electrospun amorphous solid dispersions (ASDs) were prepared and investigated from pharmaceutical application point of view. Spironolactone (SPIR) was used as model drug mixed in various concentrations with polymers suitable for fibre formation, such as vinylpyrrolidone-vinyl acetate c...

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Bibliographic Details
Main Authors: E. Szabo, B. Demuth, B. Nagy, K. Molnar, A. Farkas, B. Szabo, A. Balogh, E. Hirsch, Gy. Marosi, Z. K. Nagy
Format: Article
Language:English
Published: Budapest University of Technology 2018-05-01
Series:eXPRESS Polymer Letters
Subjects:
Online Access:http://www.expresspolymlett.com/letolt.php?file=EPL-0008881&mi=cd