Legumain Promotes Atherosclerotic Vascular Remodeling

Legumain Promotes Atherosclerotic Vascular Remodeling

Legumain, a recently discovered cysteine protease, is increased in both carotid plaques and plasma of patients with carotid atherosclerosis. Legumain increases the migration of human monocytes and human umbilical vein endothelial cells (HUVECs). However, the causal relationship between legumain and...

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Bibliographic Details
Main Authors: Nana Ozawa, Yuki Sato, Yukari Mori, Hiroko Masuda, Mao Yamane, Yuka Yamamoto, Remina Shirai, Rena Watanabe, Kengo Sato, Yusaku Mori, Tsutomu Hirano, Takuya Watanabe
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
legumain
atherosclerosis
neointimal thickness
remodeling
macrophage
VSMC
ECM
Online Access:https://www.mdpi.com/1422-0067/20/9/2195

Internet

https://www.mdpi.com/1422-0067/20/9/2195

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