Protein Expression Profiling Identifies Key Proteins and Pathways Involved in Growth Inhibitory Effects Exerted by Guggulsterone in Human Colorectal Cancer Cells

Protein Expression Profiling Identifies Key Proteins and Pathways Involved in Growth Inhibitory Effects Exerted by Guggulsterone in Human Colorectal Cancer Cells

Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such as obesity, hyperlipidemia, diabetes, and arthritis. In the current study, an...

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Bibliographic Details
Main Authors: Rari Leo, Lubna Therachiyil, Sivaraman K. Siveen, Shahab Uddin, Michal Kulinski, Joerg Buddenkotte, Martin Steinhoff, Roopesh Krishnankutty
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
colorectal cancer
hct 116
sw620
guggulsterone
label-free shotgun proteomics
intrinsic apoptosis pathway
nf-kb signaling
Online Access:https://www.mdpi.com/2072-6694/11/10/1478

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https://www.mdpi.com/2072-6694/11/10/1478

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