Dual Delivery of bFGF- and NGF-Binding Coacervate Confers Neuroprotection by Promoting Neuronal Proliferation

Dual Delivery of bFGF- and NGF-Binding Coacervate Confers Neuroprotection by Promoting Neuronal Proliferation

Background/Aims: Basic fibroblast growth factor (bFGF) and nerve growth factor (NGF) are essential for proper development, survival, growth, and maintenance of neurons in the central and peripheral nervous systems. However, because bFGF and NGF have short half-life and rapid diffusion rate, they hav...

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Bibliographic Details
Main Authors: Yanqing Wu, Zhouguang Wang, Pingtao Cai, Ting Jiang, Yiyang Li, Yuan Yuan, Rui Li, Sinan Khor, Yingfeng Lu, Jian Wang, Daqing Chen, Qiqiang Zeng, Ruisheng Zhong, Hongyu Zhang, Yuan Lin, Xiaokun Li, Jian Xiao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Basic fibroblast growth factor (bFGF)
Nerve growth factor (NGF)
[PEAD:heparin] coacervate
Neurodegenerative diseases
PC12 cells
SH-SY5Y cells
Online Access:https://www.karger.com/Article/FullText/490139

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https://www.karger.com/Article/FullText/490139

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