Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

During embryogenesis, chromatin accessibility profiles control lineage-specific gene expression by modulating transcription, thus impacting multipotent progenitor states and subsequent fate choices. Subsets of cardiac and pharyngeal/head muscles share a common origin in the cardiopharyngeal mesoderm...

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Bibliographic Details
Main Authors: Claudia Racioppi, Keira A Wiechecki, Lionel Christiaen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
chordate
CRISPR/Cas9
heart
Pharyngeal muscle
ATAC-seq
enhancer
Online Access:https://elifesciences.org/articles/49921

Internet

https://elifesciences.org/articles/49921

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