Relationship between LTR methylation and gag expression of HIV-1 in human spermatozoa and sperm-derived embryos.

OBJECTIVE: Studying the methylation status of long terminal repeats (LTR) and its relationship to gag expression of HIV-1 in order to explore regulation mechanism of HIV-1 gene expression in vertical transmission from sperm to embryo. METHODS/PRINCIPAL FINDINGS: Sperm samples were collected from a h...

Full description

Bibliographic Details
Main Authors: FangZheng Li, LianBing Li, Ying Zhong, QingDong Xie, JiHua Huang, XiangJin Kang, Dian Wang, Lan Xu, TianHua Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557281?pdf=render