Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways

Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways

Kirenol (KRL) is a biologically active substance extracted from Herba Siegesbeckiae. This natural type of diterpenoid has been widely adopted for its important anti-inflammatory and anti-rheumatic properties. Despite several studies claiming the benefits of KRL, its cardiac effects have not yet been...

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Bibliographic Details
Main Authors: Abdullah M. Alzahrani, Peramaiyan Rajendran, Vishnu Priya Veeraraghavan, Hamza Hanieh
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
doxorubicin
kirenol
Nrf2
H9c2
hypertrophy
cardiotoxicity
Online Access:https://www.mdpi.com/1422-0067/22/6/3269

Internet

https://www.mdpi.com/1422-0067/22/6/3269

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