Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice

Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice

Background/Aims: To investigate the renal phenotype under conditions of an activated renal ET-1 system in the status of nitric oxide deficiency, we compared kidney function and morphology in wild-type, ET-1 transgenic (ET+/+), endothelial nitric oxide synthase knockout (eNOS-/-) and ET+/+eNOS-/- mic...

Full description

Bibliographic Details
Main Authors: Oleg Tsuprykov, Lyubov Chaykovska, Axel Kretschmer, Johannes-Peter Stasch, Thiemo Pfab, Katharina Krause-Relle, Christoph Reichetzeder, Philipp Kalk, Jerzy Adamski, Berthold Hocher
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Chronic kidney disease
Endothelial nitric oxide synthase
Endothelin
Mice
Nitric oxide
Online Access:http://www.karger.com/Article/FullText/438516

Internet

http://www.karger.com/Article/FullText/438516

Similar Items