STING is required for host defense against neuropathological West Nile virus infection.

West Nile Virus (WNV), an emerging and re-emerging RNA virus, is the leading source of arboviral encephalitic morbidity and mortality in the United States. WNV infections are acutely controlled by innate immunity in peripheral tissues outside of the central nervous system (CNS) but WNV can evade the...

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Main Authors: Kathryn McGuckin Wuertz, Piper M Treuting, Emily A Hemann, Katharina Esser-Nobis, Annelise G Snyder, Jessica B Graham, Brian P Daniels, Courtney Wilkins, Jessica M Snyder, Kathleen M Voss, Andrew Oberst, Jennifer Lund, Michael Gale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007899