Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells

Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells

The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly reviewed. Heparin isolated from shrimp mimics the pharmacological activities o...

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Bibliographic Details
Main Authors: H.B. Nader, M.A.S. Pinhal, E.C. Baú, R.A.B. Castro, G.F. Medeiros, S.F. Chavante, E.L. Leite, E.S. Trindade, S.K. Shinjo, H.A.O. Rocha, I.L.S. Tersariol, A. Mendes, C.P. Dietrich
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
heparin, anticlotting activity
heparan sulfate, antithrombotic activity
low molecular weight heparins, preparation and antithrombotic activity
antithrombotic agents, development for clinical use
crustacean heparin-like compounds, antithrombotic activity
antithrombotic agents
vascular endothelial cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600002

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600002

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