Overexpression of the Transcriptional Regulator WOR1 Increases Susceptibility to Bile Salts and Adhesion to the Mouse Gut Mucosa in Candida albicans

The transcriptional regulator Wor1 has been shown to induce the GUT transition, an environmentally triggered process that increases the fitness of Candida albicans in the mouse gastrointestinal tract. We have developed strains where the expression of this gene is driven from the strong and tightly r...

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Bibliographic Details
Main Authors: Daniel Prieto, Elvira Román, Rebeca Alonso-Monge, Jesús Pla
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
GUT
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00389/full