Chronic Glucocorticoid Exposure Induces Depression-Like Phenotype in Rhesus Macaque (Macaca Mulatta)

It has long been observed in humans that the occurrence of depressive symptoms is often accompanied by the dysfunction of hypothalamic-pituitary-adrenal (HPA) axis. The rodent experiments also showed that chronic corticosterone exposure could induce depression-like phenotype. However, rodents are ph...

Full description

Bibliographic Details
Main Authors: Dongdong Qin, Zhifei Li, Zhaoxia Li, Limin Wang, Zhengfei Hu, Longbao Lü, Zhengbo Wang, Yun Liu, Yong Yin, Zhaofu Li, Xintian Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00188/full