Development of a Gas-Tight Microfluidic System for Raman Sensing of Single Pulmonary Arterial Smooth Muscle Cells Under Normoxic/Hypoxic Conditions

Development of a Gas-Tight Microfluidic System for Raman Sensing of Single Pulmonary Arterial Smooth Muscle Cells Under Normoxic/Hypoxic Conditions

Acute hypoxia changes the redox-state of pulmonary arterial smooth muscle cells (PASMCs). This might influence the activity of redox-sensitive voltage-gated K+-channels (Kv-channels) whose inhibition initiates hypoxic pulmonary vasoconstriction (HPV). However, the molecular mechanism of how hypoxia&...

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Bibliographic Details
Main Authors: Fenja Knoepp, Joel Wahl, Anders Andersson, Johan Borg, Norbert Weissmann, Kerstin Ramser
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Sensors
Subjects:
hypoxia
microfluidic system
Raman spectroscopy
redox reactions on single cell level
Online Access:http://www.mdpi.com/1424-8220/18/10/3238

Internet

http://www.mdpi.com/1424-8220/18/10/3238

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