Viral uncoating is directional: exit of the genomic RNA in a common cold virus starts with the poly-(A) tail at the 3'-end.

Upon infection, many RNA viruses reorganize their capsid for release of the genome into the host cell cytosol for replication. Often, this process is triggered by receptor binding and/or by the acidic environment in endosomes. In the genus Enterovirus, which includes more than 150 human rhinovirus (...

Full description

Bibliographic Details
Main Authors: Shushan Harutyunyan, Mohit Kumar, Arthur Sedivy, Xavier Subirats, Heinrich Kowalski, Gottfried Köhler, Dieter Blaas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3617019?pdf=render