Voxel-based analysis unveils regional dose differences associated with radiation-induced morbidity in head and neck cancer patients

Abstract The risk of radiation-induced toxicity in patients treated for head and neck (HN) cancer with radiation therapy (RT) is traditionally estimated by condensing the 3D dose distribution into a monodimensional cumulative dose-volume histogram which disregards information on dose localization. W...

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Bibliographic Details
Main Authors: Serena Monti, Giuseppe Palma, Vittoria D’Avino, Marianna Gerardi, Giulia Marvaso, Delia Ciardo, Roberto Pacelli, Barbara A. Jereczek-Fossa, Daniela Alterio, Laura Cella
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07586-x