The Role of Autologous Stem-Cell Transplantation in High-Risk Neuroblastoma Consolidated by anti-GD2 Immunotherapy. Results of Two Consecutive Studies

The Role of Autologous Stem-Cell Transplantation in High-Risk Neuroblastoma Consolidated by anti-GD2 Immunotherapy. Results of Two Consecutive Studies

Background: Treatment of HR-NB comprise induction, consolidation with autologous stem cell transplant (ASCT) followed by anti-GD2 immunotherapy and isotretinoin. Childrens Oncology Group and SIOPEN studies used dinutuximab and cytokines to treat patients in complete remission or refractory Bone/Bone...

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Bibliographic Details
Main Authors: Jaume Mora, Alicia Castañeda, Miguel A. Flores, Vicente Santa-María, Moira Garraus, Maite Gorostegui, Margarida Simao, Sara Perez-Jaume, Salvador Mañe
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
neuroblastoma
autologous stem cell transplantation
overall survival
event-free survival
sargramostim
anti-GD2 antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.575009/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.575009/full

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