Dopamine and α-synuclein dysfunction in Smad3 null mice

Dopamine and α-synuclein dysfunction in Smad3 null mice

<p>Abstract</p> <p>Background</p> <p>Parkinson's disease (PD) is characterized by dopaminergic neurodegeneration in the substantia nigra (SN). Transforming growth factor-β1 (TGF-β1) levels increase in patients with PD, although the effects of this increment remain...

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Bibliographic Details
Main Authors: Casarejos M José, Cuartero M Isabel, Giráldez-Pérez Rosa M, Tapia-González Silvia, Mena M Ángeles, Wang Xiao-Fan, Sánchez-Capelo Amelia
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Molecular Neurodegeneration
Subjects:
Smad3
Parkinson's disease
Synucleinopathy
Dopamine
Astrocytes
TGF-β
α-Synuclein
MAO-B
MAPK
Online Access:http://www.molecularneurodegeneration.com/content/6/1/72

Internet

http://www.molecularneurodegeneration.com/content/6/1/72

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