Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia.

BACKGROUND:Placental protein expression plays a crucial role during pregnancy. We hypothesized that: (1) circulating levels of pregnancy-associated, placenta-related proteins throughout gestation reflect the temporal progression of the uncomplicated, full-term pregnancy, and can effectively estimate...

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Main Authors: Shiying Hao, Jin You, Lin Chen, Hui Zhao, Yujuan Huang, Le Zheng, Lu Tian, Ivana Maric, Xin Liu, Tian Li, Ylayaly K Bianco, Virginia D Winn, Nima Aghaeepour, Brice Gaudilliere, Martin S Angst, Xin Zhou, Yu-Ming Li, Lihong Mo, Ronald J Wong, Gary M Shaw, David K Stevenson, Harvey J Cohen, Doff B Mcelhinney, Karl G Sylvester, Xuefeng B Ling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230000