H55N polymorphism is associated with low citrate synthase activity which regulates lipid metabolism in mouse muscle cells.

The H55N polymorphism in the Cs gene of A/J mice has been linked to low activity of the enzyme in skeletal muscles. The aim of the study was to test this hypothesis and examine effects of low citrate synthase (CS) activity on palmitate metabolism in muscle cells. Results of the study showed that car...

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Bibliographic Details
Main Authors: Brendan M Gabriel, Mustafa Al-Tarrah, Yosra Alhindi, Audrius Kilikevicius, Tomas Venckunas, Stuart R Gray, Arimantas Lionikas, Aivaras Ratkevicius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5667803?pdf=render