DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases

Abstract Dual-specificity phosphatases (DUSPs) are a subset of protein tyrosine phosphatases (PTPs), many of which dephosphorylate the residues of phosphor-serine/threonine and phosphor-tyrosine on mitogen-activated protein kinases (MAPKs), and hence are also referred to as MAPK phosphatases (MKPs)....

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Bibliographic Details
Main Authors: Tao Ding, Ya Zhou, Runying Long, Chao Chen, Juanjuan Zhao, Panpan Cui, Mengmeng Guo, Guiyou Liang, Lin Xu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-019-0329-4