Role of Natural Autoantibodies (NAA) and Natural IgM Anti-leucocyte autoantibodies (IgM-ALA) in Health and Disease
We review how polyreactive natural IgM autoantibodies (IgM-NAA) protect the host from invading micro-organisms and host neo-antigens that are constantly being produced by oxidation mechanisms and cell apoptosis. Secondly, we discuss how IgM-NAA and IgM-ALA inhibits auto-immune inflammation by anti-...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-06-01
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| Series: | Frontiers in Immunology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00198/full |