MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor.

MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor.

Glioblastomas (GBM), the most common and aggressive type of malignant glioma, are characterized by increased invasion into the surrounding brain tissues. Despite intensive therapeutic strategies, the median survival of GBM patients has remained dismal over the last decades. In this study we examined...

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Bibliographic Details
Main Authors: Hae Kyung Lee, Ariel Bier, Simona Cazacu, Susan Finniss, Cunli Xiang, Hodaya Twito, Laila M Poisson, Tom Mikkelsen, Shimon Slavin, Elad Jacoby, Michal Yalon, Amos Toren, Sandra A Rempel, Chaya Brodie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563647?pdf=render

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http://europepmc.org/articles/PMC3563647?pdf=render

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