Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol

Oxidized LDL (OxLDL) is composed of many potentially proatherogenic molecules, including oxysterols. Of the oxysterols, 7-ketocholesterol (7-KC) is found in relatively large abundance in OxLDL, as well as in atherosclerotic plaque and foam cells in vivo. Although there is evidence that 7-KC activate...

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Bibliographic Details
Main Authors: John M. Hayden, Libuse Brachova, Karen Higgins, Lewis Obermiller, Alex Sevanian, Srikrishna Khandrika, Peter D. Reaven
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301838