Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion through Paracrine Factors

Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion through Paracrine Factors

Abdominal aortic aneurysm (AAA) is a potentially lethal disease associated with immune activation-induced aortic degradation. We hypothesized that xenotransplantation of human adipose-derived stem cells (hADSCs) would reduce aortic inflammation and attenuate expansion in a murine AAA model. Modulato...

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Bibliographic Details
Main Authors: Jie Xie, Thomas J. Jones, Dongni Feng, Todd G. Cook, Andrea A. Jester, Ru Yi, Yameena T. Jawed, Clifford Babbey, Keith L. March, Michael P. Murphy
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368916X692212

Internet

https://doi.org/10.3727/096368916X692212

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