Structure-Function Elucidation of a New α-Conotoxin, MilIA, from <i>Conus milneedwardsi</i>

Structure-Function Elucidation of a New α-Conotoxin, MilIA, from <i>Conus milneedwardsi</i>

The a-Conotoxins are peptide toxins that are found in the venom of marine cone snails and they are potent antagonists of various subtypes of nicotinic acetylcholine receptors (nAChRs). Because nAChRs have an important role in regulating transmitter release, cell excitability, and neuronal integratio...

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Bibliographic Details
Main Authors: Steve Peigneur, Prabha Devi, Andrea Seldeslachts, Samuthirapandian Ravichandran, Loïc Quinton, Jan Tytgat
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Marine Drugs
Subjects:
cone snail toxins
conopeptide
α-conotoxin
drug development
electrophysiology
ion channel diseases
nicotinic acetylcholine receptor
Online Access:https://www.mdpi.com/1660-3397/17/9/535

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https://www.mdpi.com/1660-3397/17/9/535

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