The synthesis of polyfluoroalkyl substituted pyrroles as building blocks for obtaining fluorinated pyrrolidine-containing alkaloids

Aim. To study the synthetic potential of cyclization of N-(β-polyfluoroacyl)vinyl derivatives of proline and N-substituted glycines into polyfluoroalkyl pyrroles, which are useful intermediates to fluorinated pyrrolidine alkaloids. Results and discussion. N-(β-Polyfluoroacyl)vinyl derivatives of...

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Bibliographic Details
Main Authors: Anton A. Klipkov, Alexander E. Sorochinsky, Karen V. Tarasenko, Igor I. Gerus
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2020-05-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
Online Access:http://ophcj.nuph.edu.ua/article/view/ophcj.20.199953/206029