Induced pluripotent stem cell models of myeloid malignancies and clonal evolution

Reprogramming of cells from patients with genetic disorders to pluripotency is a promising avenue to understanding disease biology. A number of induced pluripotent stem cell (iPSC) models of inherited monogenic blood disorders have been reported over the past decade. However, the application of iPSC...

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Bibliographic Details
Main Authors: Andreea Reilly, Sergei Doulatov
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Stem Cell Research
Subjects:
HSC
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121000416