Dosing characteristics of oral treprostinil in real-world clinical practice

Pharmacokinetic studies with oral treprostinil demonstrate that three times daily (TID) dosing reduces peak-to-trough plasma trepostinil fluctuations compared with twice daily (BID) dosing. TID dosing may allow for faster titration, higher total daily doses, and potentially improve the tolerability...

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Bibliographic Details
Main Authors: Vijay P. Balasubramanian, Chad R. Messick, Meredith Broderick, Andrew C. Nelsen
Format: Article
Language:English
Published: SAGE Publishing 2018-07-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894018770654