Outer Membrane Structural Defects in Salmonella enterica Serovar Typhimurium Affect Neutrophil Chemokinesis but Not Chemotaxis

Neutrophils are the first responders to invading pathogens; thus, understanding their migratory response to live pathogens is crucial. We developed a microfluidic assay that separates bacteria from phagocytic neutrophils while maintaining chemical communication between the two populations...

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Bibliographic Details
Main Authors: Eric J. Leaman, Alvin Aung, Alexie J. Jacques, Bahareh Behkam
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.01012-20