Growth Arrest-Specific Gene 6 Administration Ameliorates Sepsis-Induced Organ Damage in Mice and Reduces ROS Formation In Vitro

Growth Arrest-Specific Gene 6 Administration Ameliorates Sepsis-Induced Organ Damage in Mice and Reduces ROS Formation In Vitro

Sepsis is a widespread life-threatening disease, with a high mortality rate due to inflammation-induced multiorgan failure (MOF). Thus, new effective modulators of the immune response are urgently needed to ameliorate the outcome of septic patients. As growth arrest-specific gene 6 (Gas6)/Tyro3, Axl...

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Bibliographic Details
Main Authors: Livia Salmi, Francesco Gavelli, Filippo Patrucco, Mattia Bellan, Pier Paolo Sainaghi, Gian Carlo Avanzi, Luigi Mario Castello
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
sepsis
Gas6
TAM receptors
organ damage
Online Access:https://www.mdpi.com/2073-4409/10/3/602

Internet

https://www.mdpi.com/2073-4409/10/3/602

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