Use of RUNX2 Expression to Identify Osteogenic Progenitor Cells Derived from Human Embryonic Stem Cells

We generated a RUNX2-yellow fluorescent protein (YFP) reporter system to study osteogenic development from human embryonic stem cells (hESCs). Our studies demonstrate the fidelity of YFP expression with expression of RUNX2 and other osteogenic genes in hESC-derived osteoprogenitor cells, as well as...

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Bibliographic Details
Main Authors: Li Zou, Fahad K. Kidwai, Ross A. Kopher, Jason Motl, Cory A. Kellum, Jennifer J. Westendorf, Dan S. Kaufman
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000296