LoTo: a graphlet based method for the comparison of local topology between gene regulatory networks

One of the main challenges of the post-genomic era is the understanding of how gene expression is controlled. Changes in gene expression lay behind diverse biological phenomena such as development, disease and the adaptation to different environmental conditions. Despite the availability of well-est...

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Bibliographic Details
Main Authors: Alberto J. Martin, Sebastián Contreras-Riquelme, Calixto Dominguez, Tomas Perez-Acle
Format: Article
Language:English
Published: PeerJ Inc. 2017-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3052.pdf